skip menus and go right to content

 SEARCH

 LifeWatch

LifeWatch Employee Assistance Program
1-800-333-6228
Or
TTT/TTY
1-800-745-5555


 RESOURCES


 MORE


 

HOME TOPICS NEWS READING ABOUT HELP
 
 
Schizophrenia - Matching Maternal-Fetal Genes Increase Schizophrenia Risk
Topic Home  Related:  
Matching Maternal-Fetal Genes Increase Schizophrenia Risk
(HealthDay News)
by -- Alka Agrawal
Updated: Sep 7th 2006

new article illustration

THURSDAY, Sept. 7 (HealthDay News) -- Females whose human leukocyte antigen (HLA) gene matches their mother's have a nearly twofold higher risk of developing schizophrenia, according to a study in the October issue of the American Journal of Human Genetics.

Christina G.S. Palmer, M.D., from the University of California Los Angeles, and colleagues examined the HLA genotypes of 274 Finnish mothers who had at least one offspring with schizophrenia or a related spectrum disorder and 484 affected offspring.

The researchers found that females whose HLA-B gene matched their mother's were at 1.7-fold higher risk of developing schizophrenia.

"Because the matching effect could be associated with pregnancy complications rather than with schizophrenia per se, these findings are consistent with the neurodevelopmental hypothesis of schizophrenia and with accumulating evidence that the prenatal period is involved in the origins of this disease," Palmer and colleagues conclude.

Abstract
Full Text (subscription or payment may be required)

 

 BASIC INFORMATION

 DETAILED INFORMATION

 NEWS

 LINKS

 BOOK REVIEWS